Harold Grosjean is a D.Phil student in Structural Biology at the University of Oxford and the Diamond Light Source under the supervision of Prof Phil Bigging (Oxford University) and Prof Frank von Delft (Diamond Light Source) and has a deep interest in Structure-Based Drug Design. Harold is also a visiting student at the Sloan Kettering cancer research center in New York where he worked on isothermal titration calorimetry of protein-fragment systems to validate his models with Prof. John Chodera.